Custom Peptides
Cayman Chemical DID4chLRobenzensulfonAT 10mg
A lipophilic fluorescent probe; rapidly incorporated into phospholipid cell membranes; has been used to label the plasma membrane and endocytic organelles in bovine aorta endothelial cells and rat hippocampal slices; has been used to assess proliferation in prostate cancer cell lines by flow cytometry; ex/em = 650/670 nm, respectively
Cayman Chemical DIoctnoyl Glycol 10mg
A DGK inhibitor (Ki = 58 μM); reduces basal and thrombin-stimulated phosphatidic acid levels in washed isolated human platelets at 30, 100, and 500 μM
Cayman Chemical 3 4-DmAhydrochlorIde 10mg
An MDMA analog that appears to act as a serotonin-norepinephrine-dopamine releasing agent binding to and inhibiting uptake at noradrenalin and serotonin transporters (Kis = 22.8 and 7.7 μM and IC50s = 253.4 and 108 μM, respectively); significantly less potent than MDMA; intended for forensic and research applications
Cayman Chemical ErtapenmsodIum salt 10mg
A long-acting, broad-spectrum antibiotic that is effective against Gram-positive and Gram-negative bacteria
Cayman Chemical DelavIrdInmesylate 10mg
A NNRTI; selectively inhibits HIV-1 reverse transcriptase over DNA polymerase α and δ in vitro (IC50s = 0.26, 440, and >550 μM, respectively); blocks replication of 25 primary HIV-1 isolates (mean ED50 = 0.066 μM); inhibits growth of L. infantum promastigotes (IC50 = 26.1 μM)
Cayman Chemical Aloe-emodIn 10mg
Functions as a potent laxative by inducing chloride secretion in colonic mucosa and releasing acetylcholine, which stimulates contraction of intestinal smooth muscle; also demonstrates anti-tumor activity (ED50s = 1-13 µM), inducing apoptosis in various cancer cells
Cayman Chemical LY2228820mesylate 10mg
A potent inhibitor of p38α MAP kinase (IC50 = 7 nM for human recombinant p38α); inhibits LPS-induced TNF-α production in murine peritoneal macrophages and reduces phosphorylation of MK2 in RAW 264.7 cells (IC50s = 5.2 and 34.3 nM, respectively); inhibits TNF-α production in LPS-treated mice and reduces paw swelling and cartilage destruction in a rat model of chronic inflammation (TMED50s = <1, 1.5, and 1.5 mg/kg, respectively)
Cayman Chemical BenocyclIdIn-d10 10mg
An internal standard for the quantification of benocyclidine by GC- or LC-MS